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Gastric carcinoma is one of the most common cancers worldwide. If the tumor is resectable, surgical approach is the only treatment which might have a curative intent. Even though, the majority of patients suitable for surgery will have recurrent disease, either as local recurrence or as distant metastasis. In order to improve the prognosis of these patients, there has been a crescent interest in the use of antineoplasic treatment before surgery. This article intends to review the evidence towards the use of chemotherapy, radiotherapy and chemoradiotherapy in the neoadjuvant setting.
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Gastric carcinoma is one of the most common cancers worldwide. If the tumor is resectable, surgical approach is the only treatment which might have a curative intent. Even though, the majority of patients suitable for surgery will have recurrent disease, either as local recurrence or as distant metastasis. In order to improve the prognosis of these patients, there has been a crescent interest in the use of antineoplasic treatment before surgery. This article intends to review the evidence towards the use of chemotherapy, radiotherapy and chemoradiotherapy in the neoadjuvant setting.
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